aminophylline infusion calculation

Infusion rates were adjusted based to keep serum theophylline levels within a predefined range in nine studies 21 23 26 28 30 32 34 In two studies 28 32 serum theophylline levels were factored into. Court Rules That States Medical Malpractice Act Can Apply to Nonpatients.

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B Calculate the Infusion Rate of Aminophylline Solution 1mgml The usual dose range as stated in the BNFC1 and SORT2 guidelines.

. Per dose 5 mgkg to be followed by intravenous infusion. So 06x106ml Im pretty confident 6ml would be your answer. Under 12 Years 1 milligramkghour 12-17 years 05 to 07 milligramkghour Therefore the maintenance infusion rate range in ml per hour can be calculated as follows Required Dose Weight kg Infusion Rate.

Aminophylline Injection BP may be given by slow intravenous injection or intravenous infusion in glucose injection or sodium chloride injection. To find the concentration. Rate 05 mgkghour rate is half patients weight see table below Dose and rate of aminophylline 1 mgml infusion Patient weight - kg use IBW if patient obese Dose mghr Infusion rate mlhr 40 20 20.

Serious side effects may be more likely in older adults. The results of therapeutic drug monitoring TDM factored into aminophylline dosage calculations in the majority of studies. Therapeutic serum concentrations of theophylline are considered to range from 10 to 20 mcgml and levels.

Comments-Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required. Severe acute asthma in patients not previously treated with theophyllinefor aminophylline. 38 mgkg q 4 hr 3 doses.

Precription for IV aminophylline 350mg in 100ml to be given over 30 minutes. Typically after steady-state is achieved with the intravenous aminophylline infusion the following procedure is used to calculate the oral theophylline dose. 38 mgkg q 6 hr 2 doses.

Aminophylline infusion rate mghour is multiplied by 24 to yield total daily dose of aminophylline. A calculator used to determine the appropriate dosage of Theophylline. I always clarify every dose calculation with.

Usual range is 6001600 mgday PO in three to four divided doses. 1 mL 500 X 50000 so X 100 mcgmL. 5mgkg 5mg x 70kg 350mg- add to 100ml of infusion fluid and administer over 20 minutes Maintenance Dose.

38 mgkg q 6 hr. The nurse needs to calculate how many mLh the IV pump needs to be set at. If we have 50 mg in 500 mL by moving our decimal point three spots to the right we have 50000 mcg in 500 mL.

Aminophylline has a narrow therapeutic index therefore cautious dosage determination is essential. Per dose 500 mg to be followed by intravenous infusion. Reduced doses may be needed in patients with risk factors for reduced theophylline clearance eg cardiac or liver dysfunction renal.

First we have to calculate the mcg of the solution. 38 mgkg q 8 hr. 0008 x age in weeks 021 theophylline dosage in mgkghour IV.

500mg per 10ml and want 300mg. The manufacturer product information should be consulted. I dont remember proper calculations we were taught in nursing school but it makes sense to me.

Of safety even if current dosage is tolerated. Calculate initial dosage using the following equation. 500microgramskghour 500micrograms x 70kg per hour 35000microgramshr 35mg per hour Add 500mg aminophylline to 500ml infusion fluid 1mgml concentration Set rate controlled infusion pump at 35ml per hour.

The equation for infusion rate calculation is dose stated in prescription milligrams per hour times volume in syringe in millilitres divided by the amount in the syringe in milligrams equals the infusion rate millilitres per hour or. For example in non-smoking adults initiation of a constant intravenous theophylline infusion of 04 mgkghr 05 mgkghr as aminophylline at the completion of the loading dose on average will result in a steady-state concentration of. 20 to 249 Controlled No adverse reactions are present infusion rate by 25 20 to 249 Controlled Adverse reactions are present Stop infusion for 24 hours subsequent infusion rate at least 25 Adverse reactions symptoms Stop infusion for 24 hours.

Adult nonsmokers who are otherwise healthy. Dilute 500mg aminophylline in 500 mL sodium chloride 09 or glucose 5 to give a 1 mgml solution Administration. High blood sugar--increased thirst increased urination dry mouth fruity breath odor.

Intravenous aminophylline therapy was initiated by the ED house staff one to four years postgraduate. Consider if overdose treatment required. Low potassium level--leg cramps constipation irregular heartbeats fluttering in your chest numbness or tingling muscle weakness or limp feeling.

Aminophylline infusion Find mghr DO mlhr SH gmml Dosage Calculation common icu drips icu iv drips icu drips management. This dose mgday is then multiplied by 08adjustment for the ethylenediamine component of aminophyllineto yield the total. For example in non-smoking adults initiation of a constant intravenous theophylline infusion of 04 mgkghr 05 mgkghr as aminophylline at the completion of the loading dose on average will result in a steady-state concentration of.

The conventional aminophylline protocol used for group 1 patients consisted of a loading dose of 5 mgkg of body weight administered over 20 minutes followed by an infusion of 04 to 08 mgkgh. 1 mg aminophyllinekg ideal body weighthour as a constant infusion-Obtain a second serum theophylline concentration about one half-life after starting the infusion.

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